Everything about Regioselectivity totally explained
In
chemistry,
regioselectivity is the preference of one direction of
chemical bond making or breaking over all other possible directions . It can often apply to which of many possible positions a reagent will affect, such as which
proton a strong
base will abstract from an organic molecule, or where on a substituted
benzene ring a further
substituent will add.
A specific example is a
halohydrin formation reaction with
2-propenylbenzene :
»
The reaction product is a mixture of two isomers and the regioselectivity is said to be poor.
Regioselectivity in
ring-closure reactions is subject to
Baldwin's rules.
Further Information
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